Analysis of HBV detection data

#一. General: This program was used for the HBV data analysis
# need more data to improve it, a HBV expert ' s help is necessary

#二. Check data includes:
# (1) HBsAg, surface antigen (hepatitis B surface antigen);
#阳性判断被HBV感染标志之一, but negative can not rule out the occult HBV virus
# (2) Hbsab, (hepatitis B surface antibody) HBV surface antibody
# (3) HBcAg, (hepatitis B core antigen) core antigen;
# (4) HBeAg, (hepatitis B e antigen), E antigen
# (5) Hbeab, (hepatitis B e antibody) HBV e antibody
# (6) Hbv-pres1ag

#2HBV-dna

#3.12 liver function

#4. Blood routine assays (lymphocytes, leukocytes, neutral cells)
# (1) White blood cells: normal (4-10) *10 9-L, if increased--various bacterial infections, inflammation, severe burns
#如果减少脾功能亢进, hematopoietic dysfunction, radiation, drugs, chemical toxins and other causes of bone marrow suppression, malaria, typhoid,
#病毒感染, Paratyphoid.
# (2) neutrophils (neutrophil): Normal (0.1-1.5) *10 9-L. Increase: bacterial infection, inflammation;
#降低: Viral infections
# (3) lymphocyte: Normal (0.8-4.0) *10 9-L, increased: pertussis, infectious monocytes, viral infections, acute infectious lymphocytic syndrome, lymphocytic leukemia;
#降低: Immune deficiency

#三. Purpose of the program:
# (1) Description of HBV properties
# (2) Detection of occult hepatitis B virus occult HBV virus
# (3) Detection of chronic HBV virus chronic HBV
# (4) Detection of acute HBV in acute HBV virus
# (4.1) Big detection---infectious strong
# (4.2) applied detection--infectious weak
# (5) Detection of mutated HBV virus mutated HBV
# (6) Detect virus recovery period recovery period
# (7) Infection mode
# (8) Vaccine injection Counseling
# (9) Detection of immune tolerance period

#四. Words
# incubation (infectious) incubation period
#onset onset
#semen精液
#vaginal secretions Vaginal secretions
#wound exudates Wound secretion
#antigen antigen
#antibody Antibodies

Def INTRODUCTION_HBV ():
Print "" "(1) HBV is short for hepatitis B virus.\n (2) HBV was a DNA virus.\n (3) HBV is a
Species of the genus Orthohepadnavirus, which is likewise a part of the
Hepadnaviridaefamily of viruses.\n (4) HBV can causes the hepatitis B and other disease
. \ n (5) The incubation period from the time of exposure to onset of symptoms are 6 weeks to 6 months.
\ n (6) HBV is found in highest concentrations in blood and in lower concentrations
In the other body fluids (e.g., semen, vaginal secretions, and wound exudates).
\ n (7) more Information:http://en.wikipedia.org/wiki/hepatitis_b_virus \NHTTP://WWW.CHINACDC.
Cn/jkzt/crb/bdxgy/yxbdxgy/201301/t20130106_75116.htm "" "

Def TRANSIMISSION_HBV ():
Print "" "(1) blood\n (2) sex\n (3) Born by mother\n (4) damaged skin or mucous \ n (5) Body fluids\n (6) Drug injection" ""

#HBV_DNA阳性测试, if greater than 10**3, indicates positive
def hbv_dna_test (Hbv_dna_value):
If hbv_dna_value>10**3:
Hbv_dna= "P"

def DETECT_HBV (HBsAg):
#是否感染HBV
If hbsag== "P":
Detect_result=true
If hbsag== "n":
Detect_result=false
Print "Healthy,but need Hbv_dna test to check occulthepatitis B virus or mutated HBV"

Return Detect_result

def contagious_level (hbeag,hbv_dna= ""):
#HBV传染强度测试
If hbeag== "P" and hbv_dna== "P":
contagious_result= "High"

#需要进一步验证
If hbeag== "n":
contagious_result= "Low"

Return Contagious_result

def detect__occulthepatitis_b_virus (Hbsag,hbv_dna):
#逆隐性HBV病毒

If hbsag== "n" and hbv_dna== "P":
Result_occulthepatitis_b_virus=true
Elif hbsag== "n" and hbv_dna== "n":
Result_occulthepatitis_b_virus=false
Else
Print "Consult a doctor"

Return Result_occulthepatitis_b_virus

Def DETECT__MUTATED_HBV ():
#HBV病毒变异判断
Print "HBeAg positive or negative?"
Hbeag=raw_input (). Lower ()
Print "Hbeab positive or negative?"
Hbeab=raw_input (). Lower ()
Print "Hbv_dna positive or negative?"
Hbv_dna=raw_input (). Lower ()
If hbeag== "negative" or hbeag== "n" and hbeab== "positive" or hbeab== "P" and\
hbv_dna== "Positive" or hbv_dna== "P":
Print "mutated HBV infected"
Print "Need a longer time to cure"

def RECOVER_HBV (Hbsag,hbsab,hbeag,hbeab,hbcab,hbv_dna):
#免疫恢复期判断 (previously infected with HBV)

If hbsag== "n" and hbeag== "n" and hbv_dna== "n" and hbeab== "P" and hbcab== "P" and hbsab== "P":
Print "congulation! You is in recovery period! and has antibody for HBV "
Result_recover_hbv=true


Elif hbsag== "n" and hbeag== "n" and hbv_dna== "n" and hbeab== "P" and hbcab== "P" and hbsab== "n":
Print "congulation! You is in recovery period! But you had no antibody for hbv,\
Should better consult a doctor for HBV vaccine "
Result_recover_hbv=true

Else
Print "Need to consult a doctor"

Return RESULT_RECOVER_HBV

Def vaccine_consult ():
#是否接受疫苗
If RECOVER_HBV () ==true:

Print "Enter the Hbsab number:"
Hbsab_number=input ()

If hbsab_number<10:
Print "You is in the low level of the HBV protection,consult \
A doctor for HBV vaccine injection "
Else
Print "You is safe from HBV, but is careful for mutated HBV"

def hbv_status (hbsag= "", hbsab= "", hbeag= "", hbeab= "", hbcab= "", hbv_dna= "", ast=0,alt=0):
# chronic HBV Acute hepatitis B prophase
If hbsag== "P" and hbsab== "n" and hbeag== "P" and hbeab== "n" and hbcab== "n":
result= "Maybe chronic HBV infection early period"

# chronic HBV Acute hepatitis B late
If hbsag== "P" and hbsab== "n" and hbeag== "n" and hbeab== "n" and hbcab== "n":
result= "Maybe chronic HBV infection later period"

# Big Samyang, Contagious high
If hbsag== "P" and hbsab== "n" and hbeag== "P" and hbeab== "n" and hbcab== "P":
result= "Maybe Da_san_yang"

#小三阳, infectious small
If hbsag== "P" and hbsab== "n" and hbeag== "n" and hbeab== "P" and hbcab== "P":
result= "Maybe Xiao_san_yang"

def ast_devide_alt (Ast,alt):
#AST/alt ratio, the greater the ratio, the greater the liver damage
return float (AST)/alt

Def hepatitis_status ():
#相对参考, the degree of liver damage
Value_ast_devide_alt=ast_devide_alt (Ast,alt)
If value_ast_devide_alt<1:
Result_hepatitis_status= "Maybe acute hepatitis"
Else
Result_hepatitis_status= "Maybe chronic hepatitis"

Return Result_hepatitis_status

def blood_test (Wbc,lympha,neutrophil):
#测试仪器---Blood cell analyzer test (different test instrument standard parameters)
# (1) White blood cells: normal (3.5-9.5) *10 9 times L, if increased--various bacterial infections, inflammation, severe burns
#如果减少脾功能亢进, hematopoietic dysfunction, radiation, drugs, chemical toxins and other causes of bone marrow suppression, malaria, typhoid,
#病毒感染, Paratyphoid.
# (2) neutrophils (neutrophil): Normal (0.1-1.5) *10 9-L. Increase: bacterial infection, inflammation;
#降低: Viral infections
# (3) lymphocyte: Normal (0.8-4.0) *10 9-L, increased: pertussis, infectious monocytes, viral infections, acute infectious lymphocytic syndrome, lymphocytic leukemia;
#降低: Immune deficiency
If wbc<3.5* (10**9) or neutrophil<2.0* (10**9) or lympha>4.0* (10**9):
result__blood_test= "Maybe virus infection"

If wbc>9.5* (10**9) or neutrophil>1.5* (10**9):
Result__blood_test= "Maybe bacteria infection"

Return result__blood_test

#免疫耐受期 Immune Tolerence
def immune_tolerence (result_hepatitis_status,hbv_dna,result_hbv_status):
If result_hepatitis_status== "Maybe acute hepatitis", and hbv_dna== "P", and \
Result_hbv_status= "Maybe Da_san_yang":
Return True

#main ()

def main ():

#HBV_DNA_value
print "Input Hbv_dna number:"
Hbv_dna_value=input ()


#HBsAg
Print "HBsAg positive or negative?"
Hbsag=raw_input (). Lower ()
HBSAG=HBSAG[0]

#HBsAb
Print "Hbsab positive or negative?"
Hbsab=raw_input (). Lower ()
HBSAB=HBSAB[0]

#HBeAg
Print "HBeAg positive or negative?"
Hbeag=raw_input (). Lower ()
HBEAG=HBEAG[0]

#HBeAb
Print "Hbeab positive or negative?"
Hbeab=raw_input (). Lower ()
HBEAB=HBEAB[0]

#HBcAb
Print "Hbcab positive or negative?"
Hbcab=raw_input (). Lower ()
HBCAB=HBCAB[0]

#HBV_DNA
Print "Hbv_dna positive or negative?"
Hbv_dna=raw_input (). Lower ()
HBV_DNA=HBV_DNA[0]

#AST
Print "Enter the AST number:"
Ast=input ()

#ALT
Print "Enter the ALT number:"
Alt=input ()

#WBC white blood cells
Print "Enter the WBC value:"
Wbc=input ()

#lymphatic Cell lymphocytes
Print "Enter the Lympha value:"
Lympha=input ()

#neutrophil Neutral cells
Print "Enter the Neutrophil value:"
Neutrophil=input ()

Result_hepatitis_status=hepatitis_status ()

Result_hbv_status=hbv_status ()

# RESULT_RECOVER_HBV=RECOVER_HBV ()

Analysis of HBV detection data