Problems related to coexistence of Xdebug and zendOptimizer

Xdebug and zendOptimizer coexist. in apach, zend & nbsp; Optimizer and Xdebug both use zend_extension_ts to load the dynamic library. if zend & nbsp; during Optimizer and Xdebug, Xdebug and zend Optimizer coexist.
In apach, both zend Optimizer and Xdebug load the dynamic library through zend_extension_ts;
If zend Optimizer and Xdebug are used simultaneously, an error is reported;
Then try to copy the php_xdebug-2.1.2-5.2-vc6.dll to EXT, solve with the following method, but still not loading XDEBUG;
So I would like to ask you how to solve it !! Thank you !!

extension=php_xdebug-2.1.2-5.2-vc6.dll
[Xdebug]
xdebug.auto_trace=on
xdebug.collect_params=on
xdebug.collect_return=on
xdebug.trace_output_dir="c:\Temp\xdebug"
xdebug.profiler_enable=on
xdebug.profiler_output_dir="c:\Temp\xdebug"
xdebug.remote_host=127.0.0.1
xdebug.remote_port=9000
; Port number must match debugger port number in NetBeans IDE Tools > Options > PHP
xdebug.remote_handler=dbgp

[Zend]
zend_extension_manager.optimizer_ts="E:\wamp\bin\php\php5.2.9-2\Optimizer-3.3.3"
zend_extension_ts="E:\wamp\bin\php\php5.2.9-2\ZendExtensionManager.dll"

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I suggest you read this article
Xdebug 2.1.2 coexist with Zend Debugger and Zend Optimizer