2-chloro-chloromethyl thiazole

Th class= "txt-right" > common name

Structural Type	physical and chemical properties
I want to supply I want to buy	2-chloro-chloromethyl thiazole	English name	2-chloro-5-(chloromethyl) Thiazole
	cas No.	105827-91-6	Molecular weight	168.04400
	density	1.503g/cm3	boiling point	268.6ºc at 760mmHg
	Molecular formula	c4h3cl2ns	melting point	31ºc

Product use "Use one" Used as pesticide, pharmaceutical intermediates "Use two" 2-chloro-chloromethyl-Thiazole is an intermediate of insecticide and thiophene. "Use three" More

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name

[Chinese name]:	2-chloro-chloromethyl thiazole
[English name]:	2-chloro-5-(chloromethyl) thiazole
[English aliases]:	2-chloro-(chloromethyl) thiazole | ritonavir intermediates One | 2-chloro-(chloromethyl) thiazole | 2-chloro-(chloromethyl L) thiazole
[English aliases]:	2-chloro-5-chloromethylthiazole | 2-chloro-5-chloromethylthiazole

physical and chemical properties

[Density]:	1.503g/cm3
[Boiling point]:	268.6ºc at 760mmHg
[Melting Point]:	31ºc
[Molecular formula]:	C4h3cl2ns
[Molecular weight]:	168.04400
[Flash Point]:	116.3ºc
[Exact mass]:	166.93600
[PSA]:	41.13000
[LOGP]:	2.53530
[Appearance character]:	White to light yellow crystals or colorless liquids
[Vapor pressure]:	0.0126mmHg at 25°c
[Refractive index]:	1.583

MSDS

Material Safety Data Sheet Section1. Identi?cation of the substance Product Name:2-chloro-5-chloromethylthiazole Synonyms: Section2. Hazards identi?cation Harmful by inhalation, in the contact with skin, and if swallowed. Section3. Composition/information on ingredients. Ingredient Name:2-chloro-5-chloromethylthiazole CAS number:105827-91-6 Section4. First Aid measures Skin contact:immediately wash skin with copious amounts of water in least minutes while removing Contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:immediately wash skins with copious amounts of water for at least minutes. Assure adequate Ushing of the eyes by separating, the eyelids with? Ngers. If irritation persists, seek medical Attention. Inhalation:remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Ingestion:wash out mouth with copious amounts of water in least minutes. Seek medical attention. Section5. Fire? Ghting measures In the event of a-re involving this material, alone or in combination with other materials, use dry Powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions:wear suitable Personal protective equipment which performs satisfactorily and meets Local/state/nati Onal Standards. Respiratory Precaution:wear approved Mask/respirator Hand Precaution:wear Suitable gloves/gauntlets Skin protection:wear suitable protective clothing Eye Protection:wear suitable eye protection Methods for cleaning up:mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed containe R For disposal. See section 12. Environmental Precautions:do not allow material to enter drains or water courses. Section7. Handling and Storage Handling:this product should be handled only by, or under the close supervision of, those properly quali?ed In the handling and use of potentially hazardous chemicals, who should take to account the RE, Health and chemical hazard data given on this sheet. Storage:store in closed vessels. Section8. Exposure controls/personal Protection Engineering Controls:use only in a chemical fume hood. Personal Protective equipment:wear Laboratory clothing, chemical-resistant gloves and safety goggles. General Hydiene Measures:wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Appearance:not speci?ed Boiling Point:no Data Melting Point:no Data Flash Point:no Data Density:no data Molecular Formula:c4h3cl2ns Molecular weight:168.0 Section10. Stability and reactivity Conditions to Avoid:heat,? Ames and Sparks. Materials to avoid:oxidizing agents. Possible hazardous combustion Products:carbon monoxide, nitrogen oxides, hydrogen chloride, sulfur oxides. Section11. Toxicological Information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste Disposal authority, in accordance with national and regional regulations. Section14. Transportation Information Non-harzardous for air and ground transportation. Section15. Regulatory Information No Chemicals in this material is subject to the reporting requirements of SARA Title III, section 302, or have known CAS numbers this exceed the threshold reporting levels established by SARA Title III, section 313. Section 16-additional Information N/A

Security Information

[Dangerous Goods sign]:	Xi:irritant;
[Hazard Class Code]:	R36/37/38
[Safety Instructions]:	26-37
[Customs Code]:	2934100090

Synthetic lines

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52829-72-8 5-methylidene-1 ... ~78% 105827-91-6 2-chloro-chloromethyl thiazole

Literature:: Goebel, Thomas; Gsell, Laurenz; Hueter, Ottmar F.; Maienfisch, Peter; NAEF, Rudolf; O ' Sullivan, Anthony C.; Pitterna, Thomas; Rapold, Thomas; Seifert, Gottfried; Senn, Marcel; Szczepanski, Henry; Wadsworth, David J. Pesticide Science, 1999, vol. 3, p. 355-357

14214-31-4 2-chloro-propylene-based Isothiocyanate ~96% 105827-91-6 2-chloro-chloromethyl thiazole

Literature:: Wang, Qingmin; Li, Heng; Li, Yonghong; Huang, Runqiu Journal of agricultural and Food Chemistry, 2004, vol. vol, # 7 p. 1918-1922

145015-15-2 2-chloro-hydroxy-methyl thiazole ~% 105827-91-6 2-chloro-chloromethyl thiazole

Literature:: wo2008/73461 A2,; Page/page column 149; WO 2008/073461 A2

Upper and downstream products

Upstream products    9	< previous  1/3  Next
52829-72-8 5-methy Lidene-1 ... 14214-31-4 2-chloro-allyl isothiocyanate 145015-15-2 2-chloro-hydroxymethyl thiazole 196406-44-7 3-chloro-1-isot...
downstream products   6	< P id= "Xyidxul" class= "Pull-right" >< previous  1/2  next page;
339018-41-6 4-[(2-chloro-1,... 145015-15-2 2-chloro-hydroxymethyl thiazole 338393-48-9 4-[(2-chloro-1,... 120740-08-1 2-chloro-aminomethyl thiazole

Preparation"Method One"
The preparation method is to add 2-chloro-allyl isothiocyanate and solvent chloroform in the reaction flask, and then add the sulfur chloride, to maintain the internal temperature of 30 ℃, After the drip and then at room temperature reaction 2.5h, when the temperature rose to 36 ℃, after the reaction, the solvent and the residual chlorination of sulfuric acid distillation removed, residue dissolved in two chloro methane, with NaHCO3 solution and water respectively washed, dried, steamed solvent (decompression) products. The reaction equation is shown in Fig.Customs

[Customs Code]:	2934100090
[English Overview]:	2934100090. Structurally containing a non-viscous thiazole ring compound (whether or not hydrogenated). VAT Rate: 17%. Drawback rate: 9%. Regulatory conditions: None. MFN Tariff: 6.5%. General Tariff: 20%
[Declaration element]:	Name, ingredient content, use
[Summary]:	2934100090 other compounds containing a unfused thiazole ring (whether or not hydrogenated) in the structure vat:17.0% Ta x Rebate rate:9.0% Supervision Conditions:none MFN tariff:6.5% General tariff:20.0%

2-chloro-chloromethyl thiazole