British scientists discover new immunotherapy for anticancer therapies

British scientists find new therapies for new immunotherapy that mobilize patients ' immune system and white cells to eliminate mutated cancer cells and possibly eventually cure cancer

Source: Southern Metropolis Newspaper, March 05, 2016 edition: AA13 Author: he San he

An injection can cure cancer. British scientists announced March 4 that they have identified the "Achilles heel" of cancer cells (a metaphor for their "fatal weaknesses"), paving the way for a new study of "revolutionary" therapies for cancer.

British media reported that in the future, no matter what kind of cancer patients, can be personalized with the appointment of immune therapy, this new treatment allows the patient's immune system to take the initiative to kill every cancer cell. According to the report, scientists say the new treatment may be applied to clinical treatment as soon as two years later.

The British Cancer Institute (C ancer R esearch U K) Experts say the new therapies will eventually prove to be a revolutionary way to treat and even cure cancer.

Find the "Achilles heel" of a cancer cell.

The landmark study, funded by the British Cancer Institute, was conducted by cancer research experts at University College London, the Daily Mail of March 4 reported.

A spokesman for the institute said on the same day that if the new therapies were to achieve the desired effect, "it would prove to be a revolutionary new way of treating and even curing cancer".

Researchers have identified the "Achilles heel" of cancer cells, the institute said, and have brought hope for treatment and even cure cancer. The new therapies, which are expected to be applied to clinical treatment as soon as two years later, will benefit from this new treatment regardless of the stage of cancer.

The report said that despite the current medical development, cancer in the world to take the lives of millions of people every year. Even though some therapies have been hailed as "panacea", on average, these "panacea" can only prolong the patient's life for a few weeks.

Cancer researchers at University College London said they found that existing treatments had their limitations and they understood the nature of the limitations.

Cancer researchers say people often think of tumors as a bunch of identical cancer cells, but in fact they are growing and mutating.

Currently applied to the clinical treatment of cancer drugs are specifically targeted at a specific cancer cells. If the cancer cells in the growth process of a very large mutation, the original treatment of cancer drugs on the mutated cancer cells have lost their efficacy.

At the same time, even if the cancer drug is temporarily eliminated, some highly mutated cancer cells may still lurk in the patient's body, and the time will come to a comeback.

is effective for all stages of cancer.

The breakthrough for cancer researchers at University College London is that they have found new ways to pinpoint the mutations that occur in every cancer cell in the tumor.

At the same time, experts in some lung cancer patients found in the blood of the "perfect deal" with these cancerous white cells.

Experts say researchers will be taking blood from these patients in the future, nurturing the white cells in the lab, and then injecting the cultured white cells back into the patient's body.

In theory, experts say, these white cells will kill every cancer cell.

Another treatment option would be for researchers to develop a vaccine that would allow the patient's immune system to actively attack and kill cancer cells using the mutated information of cancer cells.

Experts say the treatment is particularly effective against lung cancer and skin cancer. Experts hope that patients, including breast cancer and prostate cancer, can benefit from it.

It is reported that the advantages of the new treatment is that it for all stages of cancer patients have curative effect. For terminally ill patients suffering from cancer, new therapies are certainly a particularly useful option.

Professor Charles Swandon, who collaborated with the University College in London, said: "The new therapies offer hope that we may finally be able to reverse the situation in the treatment of advanced cancer, something we particularly want to do for our patients." ”

Professor Swandon's work is partly sponsored by the charity Medical Research Foundation, The Rose Tree Trust (th erosetrees T rust).

Features

Individualized immunotherapy for treatment

What is the difference between this new therapy and the current immunotherapy that has been applied to clinical therapy?

Experts at University College London say the immune therapy that mobilizes the patient's own immune system and white blood cells to treat cancer does have a significant effect. In some cases, some patients were diagnosed with only a few months of life, but through immunotherapy, they were able to return to work and return to normal life.

Still, experts say, current immunotherapy does not apply to every patient.

"We believe that new therapies are critical to treating cancer," says Prof Swandon. In a few years, we will be implementing immunotherapy in general, just as we do today with chemotherapy. ”

However, Professor Swandon cautioned that current research is still at an early stage and has not yet been used for clinical treatment.

But Professor Swandon said that, given the history of cancer research, he hopes the findings will eventually confirm the Achilles heel of cancer.

"It's really fascinating," he said, "that the ultimate in personalised medicine is that every patient can get a unique appointment." "said Professor Swandon.

"I would be disappointed if we hadn't been able to treat patients for two years," he says. ”

"Do we think it will be effective?" I hope it will improve the patient's survival rate. If this is not possible, I will probably Ching and go to other jobs. "said Professor Swandon.

Review of Science and technology

New therapies can be expensive and effective

Professor Swandon says the nature of the new treatment, "appointment therapy", will be costly.

But the drugs currently used to treat cancer are already very expensive. It is reported that the new anticancer drugs applied to clinical treatment usually cost as much as 70,000 pounds, but these new drugs can prolong the patient two months of life.

In stark contrast, new therapies can wipe out cancer cells in the patient's body, allowing them to return to work and continue to contribute to economic development.

Professor Peter Johnson, chief clinical physician at the British Cancer Institute, said: "This amazing research provides us with an important clue as to how to use cancer patients ' own immune systems to develop special treatment options for them." ”

Prof Johnson also said the "exciting outcome of the basic research in cancer science" would make it a way for humans to cure cancer.

"Because of the ingenuity of our cancer researchers, we may have found the tools to give accurate guidance on immunotherapy, which is what the majority of patients desperately need," says Alain Vausres of the British Cancer Institute. ”

Dr. Mark Jeringer, an expert on immunotherapy at the London Cancer Institute, said the research was "exciting" but still in its early stages, and it was too early to say whether it would be effective.

"The new study shows new evidence of how mutation and evolution can cause cancer to wreak havoc, and suggests that finding ways to stop the progression of cancer is likely to be key to defeating cancer," Dr. Jeringer said. ”