Clinical manifestation of Cqs disease time: January 04, 2013 Source: original site Click: 506 times I want to comment (0) "Font: Big Small"
1. Fever and fever are the most common symptoms of Kawasaki disease, which accounts for the 94%~100% of all patients. It usually has a sudden fever, a hot or persistent fever, and a temperature of 39. C above, the average maximum temperature is up to 39~39.9℃. Antibiotic therapy is ineffective. Untreated fever lasts for 1-2 weeks, and lasts for 3, 4 weeks, and a few or even longer. The smaller the age, the longer the heat path. The treatment of immunoglobulin is often 2 days of fever. Compared with the upper respiratory tract infection, Cqs disease children without card symptoms, manifested as "dry heat", irritability, especially the small baby irritable.
2, the eye changes after the fever of bilateral conjunctival congestion quickly, 90% of the children have this symptom, bulbar conjunctival vascular dilation, congestion, pink, eyelid conjunctival congestion is rare. No secretions, conjunctival edema or corneal ulcers, and no pain. There may be a small amount of white secretions when there is secondary infection. The incidence of ocular changes was high in younger children. The use of slit lamps can be found in mild acute iris ciliary neuritis or anterior eye uveitis, but soon disappears, with little light or eye pain.
3, oral changes in oral change include:
(1) Lip redness, lipstick-like, dry, chapped, peeled and bleeding, many children's lips red can continue to heat back for a long time;
(2) Yangmei tongue, tongue red, tongue nipple protrusion, difficult and streptococcus caused by scarlet fever difference;
(3) The whole oropharyngeal mucosa diffuse congestion, most of the children pharynx swelling, congestion, no mouth ulcers and pharynx secretion.
4, rash fever after 2-4 days, can be seen in a variety of forms of the rash, the most common non-specific diffuse plaque rash-like rashes, urticaria-like rash, scarlet rash, red skin disease, erythema-like skin rash, pattern fusion rash, such as occasionally of small pus blister-like rash, no blister and scab. The rash is found in the torso and limbs, the baby perineal rash more, can be peeling. In darker skinned children, the rash is more concealed. BCG vaccination office redness is a more specific manifestation of the disease, after BCG vaccination around 1 years of high incidence, it is mainly found in the 1-year-old infants.
5, the end of the extremities changes in the 1th week after the onset of the nail or toenail pale (incomplete white nail disease), palms and feet appear erythema, hands and feet diffuse swelling, skin often tighten harder, pressure without depression. Refers to the swelling of the joints, hard edema, skin light. There is a clear dividing line between the hand and wrist or the plantar and ankle joints. Sometimes painful sclerosis occurs in the hands or feet. 2 weeks from the disease, the finger or toe nail bed skin junction appearance characteristic membranous peeling, peeling can extend to the entire palm or plantar, the "glove" or "socks" kind. Sometimes the epidermis is clustered off, exposing new normal skin below. The more severe the hard swelling, the more obvious the peeling, no pain at the peeling, and seldom see bleeding. In recent years, due to timely treatment, the time of hand-foot swelling is short, the phenomenon of typical peeling is relatively rare. After 1-2 months, the nail can have Heng Gou-like changes, serious nails become black, fall off.
6. Cervical lymph node enlargement of the neck lymph nodes is the most uncommon clinical manifestation, about 70% of the children appear, the probability is lower than other symptoms, especially the infants under l age are more rare, older children see more. Some of the children are just beginning to fever or before fever, lymph node enlargement, the next few days, other symptoms appear. Usually one-sided, with the anterior triangle of the neck to see more. lymph node diameter is greater than 1.5cm, the lymph nodes are solid without fluctuation, the surface skin can be red, no tenderness or only mild tenderness, local puncture without purulent secretion.
The above 6 main symptoms appear in the absence of a fixed sequence, sometimes several symptoms appear at the same time, sometimes within 5 days of disease appear. In addition, not every child will appear 5 or 6 clinical major manifestations, the incidence of various signs in different ages also vary, such as fever, rash in infants and children more easily appear; eyes, mouth, rash and limbs change more than the 2nd day beginning of fever, the end of the limbs peeling occurs after 10 days.
Clinical manifestations of Cqs disease
