Microsoft Office Excel cannot access the file "Xxxxxxxxxxxxx.xls". Possible causes are:

System.Runtime.InteropServices.COMException (0X800A03EC): Microsoft Office Excel cannot access files "D:\Benz\Daimler\Benz.Win\ Lshbizplanfigure.xls ". Possible causes are:

? The file name or path does not exist.
? The file is being used by another program.
? The workbook you are trying to save has the same name as the workbook that is currently open.

I was puzzled by the appearance of the problem.

And the solution is very confusing.

This solution is ...

? Windows 2008 Server x64
Please do this folder.

C:\Windows\SysWOW64\config\systemprofile\Desktop

? Windows 2008 Server x86

Please do this folder.

C:\Windows\System32\config\systemprofile\Desktop

... instead of Dcomcnfg.exe.

This operation took away office automation problems on my system.

A Desktop folder seems to is necessary in the Systemprofile folder to open file by Excel.

It disappears from Windows2008, Windows2003 had the folder,
and I do it cause this error.

That is, creating a directory named Desktop in the C:\Windows\System32\config\systemprofile and C:\Windows\SysWOW64\config\systemprofile directories solves the problem

This method does solve my problem.