Wireless mouse and keyboard set unavailable

In order to add an HTPC computer to the living room at home and use the old computer in addition to the chassis for HTPC, we bought the leibai 8300 wireless mouse and keyboard set in the Computer City to better operate HTPC, but the strange thing is: 8300 can be used on new computers and laptops, but not on HTPC computers. He contacted leibai's customer service and said it was a system problem. However, the three systems were all win7 systems installed on the same disk, which was not a system problem. HTPC machine is Asus M2N-MX motherboard, today thought it is a problem of bios, so the M2N-MX BIOS upgrade, the results still can not use wireless mouse, do you really want to buy a PCI-E USB card to use? Thank you!