Proof of concept

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Two offshore skimmers tow an Oil Containment Boom loss ss the water during an oil spill and recovery proof of concept demonstration. an Oil Containment Boom is a floating barrier, which is used to respond quickly and collect and recover offshore oil spills.
The proof of concept demonstration focused on the ability
U. S. Navy and host nation assets to quickly react and respond to hazardous materials in the waterways

AProof of concept(POC) orProof of principleIs a realization of a certain method or idea (s) to demonstrate its

Feasibility,^{[1] or a demonstration in principle, whose purpose is to verify that some concept or theory has
Potential of being used. A proof-of-concept is usually small and may or may not be complete.}

Contents [Hide] 1 Usage history 2 Examples 2.1 In filmmaking 2.2 In engineering 2.3 In business development 2.4 In security 2.5 In software development 2.6 In drug development 3 See also 4 References

[Edit]
Usage history

The appearance of the terms in News Archives suggests it might have been in common use as long ago as 1973.^[2]

One of the early definitions of the term "proof of concept" was by Bruce Carsten in the context of a "Proof concept prototype" in the column "Carsten's Corner ":

Proof-of-concept prototype is a term that (I believe) I coined in 1984. it was used to designate a circuit constructed along lines similar to an engineering prototype, but one in which the intent was only to demonstrate the feasibility
Of a new circuit and/or a fabrication technique, and was not intended to be an early version of a production design. ^[3]

The column also provided definitions for the related but distinct terms 'breadboard', 'prototype', 'engineering
Prototype', and 'brassboard '.

[Edit]
Examples [edit]
In filmmaking

Sky Captain and the world of tomorrow,
300, And
Sin CityWere all shot in front of

Greenscreen with almost all backgrounds and
Props
Computer Generated. All three used proof of concept short films.

Pixar sometimes creates short animated films that use a difficult or untested technique. Their short film
Geri's game used techniques for animation of cloth and of human facial expressions later used in
Toy Story 2. Similarly,
Pixar created several short films as proofs of concept for new techniques for water motion, sea anemone tentacles, and a slowly appearing whale in preparation for the production
Finding Nemo.

[Edit]
In engineering

In engineering and technology, a rough prototype of a new idea is often constructed as a "proof of concept". For example, a Working concept of an electrical device may be constructed using
Breadboard.
Patent Application often requires a demonstration of functionality prior to being filed. Some universities have proof concept centers to "fill the 'funding gap '" for "seed-stage investigation"
And "accelerate the specified cialization of university innovations". proof of concept centers provide "seed funding to novel, early stage research that most often wocould not be funded by any other conventional source ".^[4]

[Edit]
In business development

In the field
Business Development and
Sales, a vendor may allow a prospect customer to trial the software product. This use of proof concept helps establish viability, technical issues, and overall direction, as well as providing feedback

Budgeting and other forms of internal demo-making processes.

In these cases, the proof of concept may mean specialized
Sales Engineers will be utilized to ensure that the vendor makes a best possible effort.

[Edit]
In security

In both computer security and encryption, proof concept refers to a demonstration that in principle shows how a system may be protected or compromised, without the necessity of building a complete working vehicle for that purpose.
Winzapper was a proof of concept which possessed the bare minimum of capabilities needed to selectively remove an item from the Windows Security Log; but, it was not optimized in any way.

[Edit]
In software development

In software development, proof of concept (abbreviated POC) is often used to describe several distinct processes with different objectives and participant ipant roles:

• A proof of concept can refer to a partial solution that involves a relatively small number of users acting in business roles to establish whether the system satisfies some aspect of the requirements.
• A steel thread is a technical proof of concept that touches all of the technologies in a solution.
• By contrast, the objective of
  Proof of technology is to determine the solution to some technical problem, such as how two systems might be integrated or that a certain throughput can be achieved with a given configuration. no business users need be involved in a proof technology.
• A
  Pilot project refers to an initial roll out of a system into production, targeting a limited scope of the intended final solution. the scope may be limited by the number of users who can access the system, the business processes affected, the business partners
  Involved, or other restrictions as appropriate to the domain. the purpose of a pilot project is to test, often in a production environment, whether the system is working as it was designed while limiting business exposure.

[Edit]
In drug development

Although not suggested by natural language, and in contrast to usage in other areas,
Proof of principleAndProof of conceptAre not synonymous in drug development. A third term,
Proof of mechanisms, Is closely related and is also described here. All of these terms lack implements definitions and exact usage varies between authors, between institutions and over time. The descriptions given below are intended to be Ive ive
And practically useful.

The underlying principle is related to the use of biomarkers as surrogate endpoints in early clinical trials. See for example the introductory discussion on pages 3 to 9 of Downing's
Biomarkers and surrogate endpoints: Clinical Research and Applications.^{[5] in Early Development
It is not practical to directly measure that a drug is valid in treating the desired disease, and a surrogate endpoint is used to guide whether or not it is appropriate to proceed with further testing. for example, although it cannot be determined early
That a new Antibiotic cures patients with pneoonia, early indicators wocould include that the drug is ineffective in killing bacteria in laboratory tests, or that it uses CES temperature in infected patients-such a drug wowould merit further testing to determine
The appropriate dose and duration of treatment. A new antihypertension drug cocould be shown to reduce blood presssure, indicating that it wocould be useful to conduct more extensive testing of long-term treatment in the expectation of showing functions in Stroke
(Cerebrovascular accident) or heart attack (mycardial infarction). Surrogate endpoints are often based on laboratory blood tests or imaging investigations like X-ray or CT scan.}

Proof of mechanismsOr pom relates to the earliest stages of drug development, often pre-clinical (ie, before the drug is given to humans, or before given to research animals ). it cocould be based on showing that the drug interacts with
Intended molecular receptor or enzyme, and/or affects cell biochemistry in the desired manner and direction.

A demo-is made at this point as to whether to progress the drug into later development, or if it shoshould be dropped.

Proof of conceptOr POC refers to early clinical drug development, conventionally divided
Phase IAndPhase IIa.

Phase IIs typically conducting CTED in 10-20 healthy volunteers who are given single doses or short courses of treatment (eg, up to 2 weeks ). studies in this phase aim to show that the new drug has some of the desired clinical activity (eg, that an experimental
Antihypertensive Drug actually has some effect on elastic cing blood pressure), that it can be tolerated when given to humans, and to give guidance as to dose levels that are worthy of further study. Other
Phase IStudies aim to investigate how the new drug is absorbed, distributed, metabolised and excreted (so-called adme studies ).

Phase IIaIs typically conducting CTED in up to 100 patients with the disease of interest. studies in this phase aim to show that the new drug has a useful amount of the desired clinical activity (eg, that an experimental antihypertensive drug reduces
Blood pressure by a useful amount), that it can be tolerated when given to humans in the longer term, and to investigate which dose levels might be most suitable for eventual marketing.

A demo-is made at this point as to whether to progress the drug into later development, or if it shoshould be dropped.

Proof of principleOr pop relates to later clinical development,
Phase III, Typically extends larger numbers of patients treated at doses and durations representative of marketed use, and in between comparison to placebo and/or existing active drugs. They aim to show convincing, then signiicant evidence
Of efficacy and to give a better assessment of safety than is possible in smaller, short term studies.

A demo-is made at this point as to whether the drug is valid tive and safe, and if so an application is made to regulatory authorities (such as the US Food and Drug Administration [FDA] and the European Medicines Agency) for the drug to receive permission
To be marketed for use outside of clinical trials.

Clinical trials can continue after marketing authorisation has been already ed, for example to better delineate safety, to determine appropriate use alongside other drugs or to investigate additional uses.

[Edit]
See also

• Case Study
• Concept Vehicle
• Feasibility Study
• Prototype
• Sanity Testing
• Technology readiness level
• An example:
  Template: wikibooks-POC

[Edit]
References

1. ^
   
   Investorwords.com
2. ^
   
   News.google.com
3. ^Carsten, Bruce.
   Carsten's corner. Power Conversion and intelligent motion, November 1989, 38
4. ^
   
   Http://www.kauffman.org/uploadedFiles/POC_Centers_01242008.pdf
5. ^
   Downing, Gregory (2000 ).
   Biomarkers and surrogate endpoints: Clinical Research and Applications. Elsevier.
   
   The ISBN 0444503161.
   

   Http://books.google.com/books? Id = qrn_tcchjoqc & Pg = pa3 & LPG = pa3 & DQ = surrogate + endpoint + % 22 proof + of + concept % 22 # V = onepage & Q = surrogate % 20 endpoint % 20% 22 proof % 20of % 20 concept % 22 & F = false.

 

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POC, short for proof concept, provides evidence of opinion. It is a set of suggested electronic models that can be used to demonstrate the design of teams and customers, permits evaluation and validation of conceptual design schemes. POC evaluations may cause specification and design adjustments.

1. POC concept POC is the abbreviation of proof concept, which means to provide evidence for the viewpoint. It is a set of suggested electronic models that can be used to demonstrate the design of teams and customers, permits evaluation and validation of conceptual design schemes. POC evaluations may cause specification and design adjustments. The design commitment and comments recognized by the POC process will be recorded in the design adjustment document for future reference. In this way, POC continues to develop. If you need help when completing these tasks, you can find assistance resources at the University of Queensland.

2. POC development. The POC development steps and methods are as follows: Step 1: Develop an interface model that contains all basic navigation features (buttons, icons, menus, etc.), but it is not the final perfect form. Step 2: add a small amount of content to the interface, especially adding one or two samples to the crucial media. For example, if a package is very dependent on a 3D model, you should add a 3D model sample that contains the required driver. If the software package needs to display data symbols and tables, the data symbols and table samples should also be added. Note that this process should be used to support demonstration and verification design, rather than the actual start of software package development. You should try your best to demonstrate and sell the design, but do not go too far, because sometimes major changes are required during the design process, which will lead to a waste of resources.

3. POC evaluation and verification. The evaluation and verification process is to seek feedback from risk owners through POC and ICP filing design documents. Through POC evaluation, risk owners may propose requirements for specification adjustment and design. Sometimes the design team may have to go back to the drawing board due to design defects or inappropriate places. The customer may decide to stop the design or look for other teams because the design does not focus enough on the needs of customers and users, or because the customer's needs are unstable. Sometimes this change is caused by the customer's organization or project decision makers. Generally, at the end of the evaluation and verification process, the design commitment and comments recognized by everyone will be recorded in the design documents for record filing, this is often an important milestone in the product development lifecycle. After the evaluation and verification are completed, the POC can continue to develop.

4. minimal requirements. Although POC is an important evaluation technology in the product development process, you should also limit the time spent on POC development, taking into account all the factors included in the previous design phase, build key elements in the POC. We should put enough energy into the demonstration and design aspects, but not too much, so that even if the design requires significant changes, it will not lead to a waste of a lot of resources. Prior to the implementation of the overall design, it is necessary for the customer to recognize the design.

5. Customer Role Positioning. Specifications and design phases require detailed design documents for product development, and POC is always followed by product development. The customer signs the design document and reports the POC as an important project milestone. If the product design still needs to be modified in the next phase, it should be approved and approved according to the controlled change control process. During the entire project process, the customer's important responsibility is to ensure that the confirmed schedule is delivered on schedule, and agreed to the occurrence of the need for re-investment to prevent planned delays.