Substituted base attribute in Chembiodraw

The substituted base attribute refers to the number of substituted bases on the selected atom. In Chembiodraw software, a substituted base is defined as a non-hydrogen atom connected by any key. Instead of cardinality the atomic property allows you to specify the number of keys on an atom in the target structure, including those that the query structure has drawn. This tutorial will take the substitution base attribute in Chembiodraw software as an example to explain the use of CHEMBIODRAW query structure.

Substitution Base Sample Diagram

The options for replacing the base in the Atom Properties dialog box include the following:

Replace the base in the Atom Properties dialog box option

(1) Unspecified (indeterminate default): The action is determined by the target database. Some databases (including ISIS) will be issued. A compound of any substituted base on this atom; some databases (including DARC) will only find compounds that have exactly the substituted base they are drawn from.

(2) Free Sites: Find compounds in which the selected atoms can contain a range of substituted bases the number of options in the Quantity box plus the number of keys drawn.

(3) Up to (max.): Find compounds in which the selected atom can contain the range of substituents that is the maximum number of options in the Quantity box.

(4) Exactly (exact): Find a compound with the selected atoms that contain a specified number of substituted bases in the fine-tuning button, up to 15 substituents.

Through the above tutorial, I believe you have fully mastered the Chembiodraw software in the substitution of the base attribute, skilled use of CHEMBIODRAW query structure techniques can help users more efficient editing of chemical structure graphics.