The process account used to run ASP. NET must have read access to the IIS metabase (for example, IIS: // servername/W3SVC.

Problem presentation:
The process account used to run ASP. NET must have read access to the IIS metabase (for example, IIS: // servername/W3SVC.

Cause analysis:
This problem occurs mostly because IIS is installed after. NET Framework is installed.

Solution:
Start->Program-> Microsoft. NET Framework SDK V2.0-> SDK Command Prompt
Input
Aspnet_regiis-I press ENTER

Next, you may encounter another problem: failed to create mutex.

Solution:
Delete the original project and the new project can be properly debugged and run!