The shearing process of bioinformatics--rna

Source: Internet
Author: User

exon (exon expressed region) is part of the eukaryotic gene, which is preserved after splicing (splicing) and can be expressed as a protein in the process of protein biosynthesis.

Exon is the last gene sequence that appears in mature RNA, also known as the expression sequence. A nucleotide sequence that exists both in the original transcription product and in the mature RNA molecule. The term exon also refers to the region in the DNA that encodes the corresponding RNA exon. All exon together make up the genetic information, which is reflected in the protein.     

intron (intron) in the process of transcription, the internal nucleotide sequence removed from the original transcription product. Intron is a sequence of linear expression of blocking genes.

precursor RNA (Pre-rna) precursor precursor: a substance that is present or formed in the pre-phase of a reaction or process, which is later converted to another substance or system.

precursor of mRNA : Nuclear non-uniform RNA (hnrna,heterogeneous nuclear RNA)

The Splite gene, a eukaryotic structure of genes, is separated from each other by a number of coded and non-coded regions, but is continuously inlaid, to be able to translate a complete protein consisting of continuous amino acids, known as the fracture gene, unless the coding area is reconnected (splite Gene).

DNA is divided into coding area (coding region) and non-coding area, and the coding region is divided into exon and intron .

Cutting Process (splicing): The process of removing the intron from the initial transcription of the DNA template chain and linking the exon to form a continuous RNA molecule. The splicing of RNA is to remove the intron from the transcription of the broken gene.

RNA splicing is a very important biological process in eukaryotic cell gene expression, which can produce many functions by splicing RNA. Mrna.rna splicing identification with coded information is an important step in correctly understanding the process of gene expression, and the key of splicing recognition depends on the decision of splice site. There is a certain sequence conservatism in the splicing site of eukaryotic Pre-mrna, and for the corresponding cDNA sequence, intron 5 ' End (for postural points) and 3 ' End (receptor sites) of the base are almost all GT and AG, so called GT-AG rules

The original transcription produced by DNA transcription-the nucleus-heterogeneous RNA, the precursor of the mRNA, is cut through RNA, and the exon portion of the encoded protein is connected to a continuous readable frame (open reading frame ORF), Through the nuclear hole into the cytoplasm, it can be used as a protein synthesis template.

The shearing process of bioinformatics--rna

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