Using the Visual Studio Ultimate with Update 4 development site in Windows 10, 9926 is fine, and up to 10041 cannot be debugged:
An unhandled exception of type "System.Runtime.InteropServices.SEHException" is in an unknown module. Occurs in
Additional information: An exception occurred on the external component.
The managed debugging assistant "Fatalexecutionengineerror" detected a problem in "C:\Program Files (x86) \iis Express\iisexpress.exe".
Additional information: Run-time encountered an error. The address for this error is 0X73AD8EB4, on thread 0x21a4. The error code is 0xc0000005. This error may be a bug in the CLR, or a bug in the unsafe or non-verifiable part of user code. A common source of this bug includes user marshaling errors on Com-interop or PInvoke, which can corrupt the stack.
I replaced Visual Studio CTP 6 (Version 14.0.22609.0.d14rel) with the same situation.
Online said with Netsh winsock reset way I tried, also not, this solution should be the old version of Windows encountered situation, Win 10 under the same situation with me, and there are solutions, please reply here, look!
Windows Technical Preview 10041 running Web site application exception using IIS Express