Biofilm (5) _ Clear and suppress

Prevent

To prevent biofilm formation in certain situations, there are the following methods:

Precautionary:

• Prevent nutrients from sinking
• The special surface makes the bacteria not attached ("the effect of the law")

Physical method:

• Super Voice
• High Voltage
• Magnetic Stadium

Chemistry methods:

• Antibiotics
• Decontamination solvents.
• Hydrogen peroxide
• Chelating admixture (e.g. EDTA)

Biological control methods:

• Adding the similarity of the lure in the group sensibility and suppressing the group sense

Food: xylitol

FruA

Senpuku, a biologist at Japan's National Institute of Infectious Diseases, Tokyo, and colleagues want to know what substances have given saliva streptococcus a powerful resistance to tooth decay. The researchers used chromatography, a method of separating the various molecules in a mixture based on charge or size, to isolate different proteins from the saliva streptococcus samples. The researchers then blended each protein with Streptococcus mutans to measure which of the cultures formed the thinnest biofilm on the laboratory sheet. Protein Frua is an enzyme that decomposes complex sugars, which is the most powerful biofilm blocker.Saliva StreptococcusFruA researchers also found that a form of FruA, produced by the common fungus Aspergillus niger, is a readily available product that has the same good effect in preventing plaque formation. Although the amino acid sequence of this commercial Frua is somewhat different from that of the saliva Streptococcus frua, commercial Frua still works. Senpuku said that this could lead to the rapid development of toothpaste containing Frua.FruAThese findings are reported in the Journal of Applied and Environmental Microbiology, however, this does not mean that you are allowed to eat all the sugars you want to eat. When researchers increased the concentration of sucrose in a mixture of Streptococcus frua and Streptococcus mutans, the beneficial bacteria lost the ability to prevent biofilm formation. The authors of the study wrote that the observations could explain why a 1996 study found that Frua in mice contributed to the formation of cavities.

Mary Ellen David, a biologist at the Forsyth Institute in Cambridge, Massachusetts, agreed that the findings could lead to the development of higher quality toothpaste. However, she pointed out that the development task would not be so easy: "A huge challenge is to find a formula that will keep the enzyme active on your favorite grocery store shelves,"

Vaccination (vaccination) against oral infections (infection)

In the case of dental (dental) caries (tooth decay), proteins involved in colonization (colonization) of teeth byStreptococcus mutans variant streptococcus /c2> can produce antibodies that inhibit (suppress) the cariogenic process.

After the occurrence of cavities, the mutant streptococcus protein that breeds in the mouth can produce antibodies that protect the teeth.

Biofilm (5) _ Clear and suppress