No solution for write access to "C:\Windows\Microsoft.NET\Framework64\v4.0.30319\Temporary ASP. NET Files"

Problem situation:

Run the Web service on a 64-bit machine and then test the access after configuring it with the following prompt:

Specific view, in the C:\Windows\Microsoft.NET\Framework64\v4.0.30319 directory does not really have this file or directory, try to find someone else to give the method, all kinds of change permissions, useless.

The key point, this is in the 64-bit runtime, \framework \v4.0.30319 and \framework\v4.0.30319 directory under the same structure, the 32-bit directory under the temporary The ASP . NET Files folder is copied to the framework64\v4.0.30319 directory, and this problem does not occur when you visit the Web site.

Hope to help people who have the same problem.