KeywordsResearchers successful development pills Alzheimer's disease
A team of researchers at the Albert Einstein Medical School in centenarians found three genes that can fight old age diseases and contribute to a healthy longevity. Based on the findings, the researchers plan to develop a super pill that "replicates" the genes, helping people to eliminate the threat of Alzheimer's (Alzheimer's disease), diabetes, and heart disease, and to live a healthy life. The longevity gene researchers selected 500 German and Eastern European Jews with an average age of 100 years to collect their blood samples, extract DNA from them, and carefully compare the 2 million genetic markers. "We found that there are three of genes that occur frequently in these centenarians," "Two of these can significantly increase good cholesterol, which is an effect that no drug has achieved so far," the Daily Mail of 3rd quoted Dr. Nier Barzille, a research leader and geneticist, as saying. Another gene seems to prevent diabetes. "30% of them are overweight or obese, and 30% smoke two packs of cigarettes in more than 40 years," Barzille said, "because they have longevity genes in their bodies to protect them from the environment." "The average person is one of the most likely to live for a century, but people with long-lived genes are 20 times times more likely to live in the same life," the researchers said. Pill development Barzille says people with this particular genotype may have a 80% lower risk of developing Alzheimer's disease. In addition, the gene can also protect the body from smoking, unhealthy eating habits, obesity, lack of exercise influence. But doubts have also been raised. "Alzheimer's is the most common form of dementia, probably caused by genetic permutations, lifestyles and experiences," says Andrew Kellingham of the Alzheimer's Society. So there may be a variety of genes involved. "But Barzille is still bullish on the results," he said. "The advantage of discovering these genes is that we can develop drugs that have the same effect as them." If we can imitate their "working principle", people can enjoy a long life. "At the moment, several laboratories have begun to develop the drug. Barzille predicts that this "longevity pill" is expected to be successfully developed in 3 years and put into clinical trials. Important value Professor Judith Phillips, President of the British Society of Gerontology, says the discovery of longevity genes will change the way people think about aging. She said: "The elderly population is increasing, it (the development of longevity pills) will bring great opportunities." If older people are healthier and have longer seniority, they will become useful resources for society. Our attitude towards the elderly will be radically changed. At the same time, the cost of caring for the elderly will decrease correspondingly. Jeremy Pierson, deputy medical director of the British Heart Foundation, said: "If you're optimistic, the drug will be successful in 3 years, and it's important for people to find ways to prolong their lives." "(Han Yu)
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