Custom-made babies, ethical intolerance?

2015 China's most sensational news is the opening of a comprehensive second child, 80 after feeling that they are the only one-child, satin hands also began to play, as the only child of Gen Y couples, not only to support four parents, the future also need to take care of four grandchildren, pressure Alexander. In fact, after the policy release, the sensation is a sensation, but not everyone wants to have second child, the illusion of family life is far from the enemy but the reality of helplessness, childcare, tuition, buy a house, these things need money enough to make any couple in the time of sex, fear, cautious, the bigger problem is that Now parents want their children to become elite, so they struggle in the starting line, like what Austrian number classes, piano classes, not children like to give newspapers, in fact, they do not know that these training courses have no use, just to their laziness and ignorance to find some comfort, in fact, many people do not know the prenatal and postnatal, I do not know how to improve the personality of children, they can only find the appearance of things, short-term things, and participate in a life growth of this high-level idea, it is too difficult.

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Elite Education The most the place to complain is that it brings endless, constant comparisons, because of the prevalence of "other people's children" become China's best children, pushy parents love is still their children, but also want to customize a "other family's children," before this can only be wishful thinking, But with the maturation of gene editing technology, custom babies are getting closer to reality, in fact, this technology is theoretically absolutely feasible, and before it is really popularized, we need to consider the issues of religion, ethics and social fairness.

How to customize a favorite baby?

In fact, gene editing technology has been around for a long period of 20 years, biologists have gradually established a set of mature gene editing procedures: first, the specific DNA fragments inserted into mouse embryonic stem cells, and then the modified stem cells implanted into the early embryo (i.e. embryo sac), and finally transplanted the developing cells into the female mice. This model of gene editing, the system is mature, but it takes several years and hundreds of thousands of of the cost, Miss rate is too high, only 30% of the hit ratio, and can only be used in mice, rats and other minority species. In 2015, CRISRP, a breakthrough in gene editing technology, perfectly bypassed the operation of embryonic stem cells, making the entire gene editing process fast, precise, and highly efficient, with the ability to quickly put a gene in the right place, bypassing the stem cell operation, CRISRP not only reduces operating costs, but also greatly expands the range of application of gene editing techniques.

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In general, gene editing technology can accurately change the biological DNA, it can shut down certain genes, but also to increase the specific genes, such technology has long appeared in the film and television works, and now CRISRP technology is expected to turn it into a reality, more exciting is that its application field beyond the white mouse, Sheep or Teenage Mutant Ninja Turtles can actually be used in humans to help us overcome congenital genetic diseases, as well as to customize a baby like a set phone plan.

Now, gene editing technology, including CRISRP technology is limited to the experimental phase, its security is still in the test, the "off-target" prevention and treatment mechanisms are also under discussion. In the short term, the core application of gene editing technology will be used to correct the human gene to eliminate disease, build more life species, eliminate pathogens and so on, the application of this therapeutic purpose in line with the existing laws, religions, philosophical order, in the short term may make a major breakthrough, The world's congenital genetic diseases will be significantly reduced. Our trouble is how to look at "non-therapeutic gene editing technology", as mentioned earlier, CRISRP gene editing technology is efficient, fast, low cost, high accuracy, in the foreseeable future, will inevitably go out of the laboratory, at least in the elite spread out, at that time, human may not only satisfied with the elimination of disease , the application of the wind is to change the baby's traits, change the baby's hair, skin color, and even IQ, and these traits will be passed down from generation to generation, such as Michael Jackson want a white child, no longer need to do body skin replacement surgery, only need to change the control of the color of the gene can be, the real change in life.

Ethical, customized baby will be born smoothly?

Now, scientists on the human genetic research has two off-limits, one is not allowed to non-therapeutic fertility screening, the second is not allowed to genetically artificial editing, the reason for these two restricted areas, mainly because the scientists themselves fear, after all, gene editing there are too many uncertainties, in case of anything uncontrolled monster , the destruction of human beings is not a sinner, on the other hand, people from the political, legal, philosophical fields can not accept the "custom Baby", they are hypocritical to maintain the old order, and the hands of important social resources, minutes can cut off the funding of scientists, or open a tank, To raze the genetic-editing lab.

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As far as fairness is concerned, the genetic editor is expected to make real God in real life, strong and gentle, handsome, mild-tempered, easy to save the world, obviously, this is very unfair for the average baby, they did not lose at the starting line, but the custom baby was born directly on the finish lines ... The problem of fairness caused by gene-editing technology is sure to frustrate ordinary parents, who give their children more training courses and can't catch up with the "Custom Baby" gap, but what? The world is not fair, even if there is no genetic editing technology, the children have been a lifetime because of color, IQ and the children of his father and become different, everyone can accept this injustice, and strive to fight against fate, because of this struggle and struggle to make mankind progress, from the perspective of natural selection theory, Hard-working babies and their parents survived, while non-hardworking babies and their parents slowly disappeared, ultimately improving human quality. From this point of view, I very much support the birth of "Custom Baby", in fact, the group of mad scientists, is not due to some hypocritical arts students stop exploring, that is, custom baby will be born smoothly.

Compared to the conservative Paris conference, the Economist's opinion is that if gene-editing techniques can be proven to be safe in humans, it is necessary to fight for consent and equality. This tool, which allows humanity to live a healthier, longer-lived and better-quality life, is within reach, and it deserves to be embraced. (New discoveries of science and Technology, Constantine/Wen)

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Custom-made babies, ethical intolerance?