Because IIS 7 employs a more secure Web. config management mechanism, the configuration items are locked by default and do not allow changes. Run the command line%windir%\system32\inetsrv\appcmd unlock config-section:system.webserver/handlers.
The handlers is the name of the node in the error message that is displayed in red characters.
If modules is also locked, you can run%windir%\system32\inetsrv\appcmd unlock config-section:system.webserver/modules
Note: Cmd.exe to start as an administrator, find Cmd.exe under C:\Windows\System32, right-click Administrator to start, enter the above command.
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Win7 IIS Configuration Error: This configuration section cannot be used in this path. This behavior occurs if the section is locked at the parent level. The lock is the default setting